Glivec 400mg Tablet is a prescription medicine used to treat certain cancers, mainly chronic myeloid leukemia (CML) and gastrointestinal stromal tumors (GIST). It contains Imatinib mesylate, a targeted treatment designed to slow down or stop cancer growth.
This medicine works by blocking specific proteins that cause cancer cells to grow abnormally. In CML, it targets the BCR-ABL protein, and in GIST, it blocks the c-KIT protein. By acting mainly on cancer cells, it helps limit damage to healthy cells.
Because of this targeted action, Glivec 400mg Tablet is often easier to tolerate than traditional chemotherapy. However, regular check-ups and blood tests are still important to make sure the treatment is working safely and effectively.
Glivec 400mg Tablet is usually taken once a day with food and water to avoid stomach upset. Some people may experience side effects like nausea, diarrhea, tiredness, muscle cramps, or swelling. Rare but serious effects can occur, so it’s important to follow your doctor’s instructions and report any unusual symptoms promptly.
1. Chronic Myeloid Leukemia (CML).
2. Philadelphia chromosome-positive Acute Lymphoblastic Leukemia (Ph+ ALL).
3. Gastrointestinal Stromal Tumors (GIST).
4. Myelodysplastic/Myeloproliferative Diseases (MDS/MPD).
5. Systemic Mastocytosis.
6. Hypereosinophilic Syndrome and/or Chronic Eosinophilic Leukemia (HES/CEL).
7. Dermatofibrosarcoma Protuberans (DFSP).
Glivec 400mg Tablet contains Imatinib mesylate, a targeted cancer medicine that works by blocking abnormal proteins responsible for cancer cell growth. In chronic myeloid leukemia (CML), it stops the action of the BCR-ABL protein that causes uncontrolled growth of white blood cells. In gastrointestinal stromal tumors (GIST), it blocks the c-KIT protein, helping slow down or shrink the tumor.
Side Effects of Glivec 400mg Tablet
Serious Side Effects (Seek immediate medical attention):
Common Side Effects (Usually mild and temporary):
Glivec 1400mg Tablet should be taken exactly as prescribed by your doctor. The usual dose is 100 mg once daily, taken with food and a full glass of water to reduce stomach upset. In some cases, your doctor may adjust the dose based on your condition, response to treatment, or side effects. Do not skip doses, change the dose, or stop the medicine without medical advice. If you miss a dose, take it as soon as you remember unless it is almost time for the next dose.
Not recommended unless advised by a doctor. It is unknown if the drug passes into breast milk and could harm the baby.
Avoid alcohol while taking 400mg Tablet, as it may increase the risk of liver damage.
Limit or avoid alcohol while taking this medicine, as it may increase the risk of liver damage or side effects.
400mg Tablet may cause dizziness or fatigue in some individuals. Avoid driving or operating heavy machinery if you feel unwell.
400mg Tablet is not recommended during pregnancy unless advised by a doctor. Use effective contraception during treatment
Glivec 400mg Tablet is a targeted therapy that blocks specific proteins responsible for cancer growth, unlike chemotherapy which affects both cancerous and healthy cells. This targeted action helps reduce damage to normal cells.
The duration of treatment depends on your condition and response to therapy. Some patients may need long-term or lifelong treatment, especially for chronic conditions like CML, under regular medical supervision.
Yes, Glivec 400mg Tablet should be taken with food and water to reduce stomach irritation. However, certain medicines, supplements, or herbal products may interact with it, so always inform your doctor about everything you are taking.
Regular blood tests are needed to monitor blood counts, liver function, and overall response to treatment. Your doctor may also check for fluid retention or other side effects during follow-ups.
Glivec 400mg Tablet is not recommended during pregnancy or breastfeeding as it may harm the baby. Effective contraception should be used during treatment and for a period advised by your doctor after stopping the medicine.
If you notice severe symptoms such as unusual swelling, shortness of breath, yellowing of the skin or eyes, severe fatigue, or signs of infection, contact your doctor immediately. Early reporting helps prevent complications.
| Active ingredient | Imatinib mesylate |
| Pharmacologic class | Tyrosine Kinase Inhibitor (TKI) |
| Medication category | ANTI NEOPLASTICS |
| Dosage forms | Tablet |
The information on the Phoenix Pharmex website is shared for educational purposes only and is not a substitute for professional medical advice or treatment. Always consult a doctor for any health-related questions. Please avoid self diagnosis or delaying medical care based on this content. Our mission is to support informed decisions not replace professional medical guidance.
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