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Darzalex 400mg Injection contains Daratumumab, a targeted monoclonal antibody therapy used to treat multiple myeloma, a cancer of the bone marrow, in adults aged 18 years and above. Unlike traditional chemotherapy, this medicine works by helping the immune system identify and destroy cancer cells. Darzalex specifically targets a protein called CD38 found on multiple myeloma cells, leading to their destruction and slowing disease progression. It is commonly prescribed either alone or in combination with other anti-cancer medicines, depending on the stage of the disease and previous treatments.
This medication requires careful medical supervision as it can affect blood cell counts and may reactivate dormant infections such as hepatitis B. Patients receiving Darzalex are closely monitored for infusion-related reactions and changes in blood test results to ensure safe and effective treatment.
Darzalex 400mg Injection is used for:
It may be prescribed as monotherapy or combined with other cancer treatments based on individual clinical needs.
Darzalex works by binding to CD38, a protein highly expressed on multiple myeloma cells. Once attached, it activates the immune system to destroy these cancer cells through multiple immune pathways. This targeted action helps reduce tumor burden, slow disease progression, and improve treatment response while minimizing damage to healthy cells.
Side Effects of Darzalex 400mg Injection
Like all medications, Darzalex 400mg Injection may cause side effects. However, not everyone will experience them.
Serious Side Effects (Seek immediate medical attention):
Common Side Effects (Usually mild and temporary):
Darzalex 400mg Injection is administered only by a trained healthcare professional in a hospital or clinical setting. The dose, frequency, and duration of treatment are determined by the doctor based on disease severity, previous treatments, and overall health. Patients are monitored during and after administration for possible reactions. Self-administration is strictly not allowed.
The safety of Darzalex during breastfeeding has not been clearly established. Breastfeeding mothers should consult their doctor to carefully assess potential risks before starting or continuing treatment.
Alcohol consumption may increase the risk of drowsiness, fatigue, or other side effects while receiving Darzalex. It is advisable to limit or avoid alcohol and discuss safe consumption with your healthcare provider.
Inform your doctor if you have asthma, chronic obstructive pulmonary disease (COPD), or any other respiratory conditions, as Darzalex may increase the risk of breathing-related reactions.
This medicine may cause dizziness, fatigue, or reduced alertness. Avoid driving or operating heavy machinery until you know how your body responds to the treatment.
Darzalex should be used during pregnancy only if absolutely necessary, as it may cause harm to the unborn baby. Women of childbearing potential are advised to use effective contraception during treatment and continue it for at least 3 months after the final dose.
Darzalex is an immunotherapy, not chemotherapy. It targets the CD38 protein on multiple myeloma cells and activates the immune system to destroy cancer cells while minimizing damage to healthy cells.
Yes, Darzalex may be used as a first-line or subsequent treatment depending on disease stage, prior therapies, and overall patient health, as determined by the oncologist.
Yes. Darzalex can interfere with blood typing and cross-matching tests. Patients should inform healthcare providers and blood banks before receiving any blood transfusions.
Patients with past hepatitis B infection must inform their doctor before treatment, as Darzalex may reactivate the virus and requires close monitoring throughout therapy.
Yes. Darzalex may be used long-term under strict medical supervision. Treatment duration depends on response, tolerability, and disease progression, with regular follow-ups required.
Darzalex 400mg Injection (Daratumumab) is available through Phoenix Pharmex for patients, caregivers, and healthcare providers across India. As a trusted supplier, distributor, and wholesaler, we offer genuine Daratumumab Injection with prescription verification and cold-chain delivery. Darzalex 400mg price in India varies by pack size and availability — contact us for current pricing.
| Active ingredient | Daratumumab |
| Pharmacologic class | Monoclonal Antibody |
| Medication category | ANTI NEOPLASTICS |
| Dosage forms | Injection |
The information on the Phoenix Pharmex website is shared for educational purposes only and is not a substitute for professional medical advice or treatment. Always consult a doctor for any health-related questions. Please avoid self diagnosis or delaying medical care based on this content. Our mission is to support informed decisions not replace professional medical guidance.
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