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Imbruvica 140mg Capsule

Prescription Required
prescription

Salt Composition

Manufacturer

JOHNSON & JOHNSON PVT LTD

Origin of Medicine

United States of America

₹327000.00

    MRP:₹408750.00
Save ₹ 81750 (20%)
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Overview & Usage

Overview Of Imbruvica 140mg Capsule

Imbruvica 140mg Capsule contains Ibrutinib, a targeted cancer therapy used to treat several types of blood cancers. It is prescribed for mantle cell lymphoma (MCL), chronic lymphocytic leukemia (CLL), small lymphocytic lymphoma (SLL), Waldenström’s macroglobulinemia (WM), and marginal zone lymphoma (MZL). It is also effective in managing chronic graft-versus-host disease (cGvHD) when previous treatments have not worked.

Imbruvica works by blocking abnormal cancer cell growth and helping restore healthy immune function. Because of its targeted mechanism, it offers a more precise and convenient oral treatment option compared to traditional chemotherapy.


Usage Of Imbruvica 140mg Capsule

Imbruvica 140mg Capsule is used to treat the following conditions:

1. Treat Mantle Cell Lymphoma (MCL)

2. Manage Chronic Lymphocytic Leukemia (CLL)

3. Treat Small Lymphocytic Lymphoma (SLL)

4. Treat Waldenström’s Macroglobulinemia (WM)

5. Manage Marginal Zone Lymphoma (MZL)

6. Treat Chronic Graft vs Host Disease (cGvHD) after failure of systemic therapy

How Imbruvica 140mg Capsule Works

Imbruvica (Ibrutinib) is a targeted Bruton’s Tyrosine Kinase (BTK) inhibitor that blocks key signaling pathways cancer cells rely on to grow and survive. By interrupting these signals, it slows disease progression, promotes programmed cell death (apoptosis), and helps reduce overall tumor burden. Its precise action on abnormal cells allows for effective, long-term disease control through convenient oral therapy.


Side Effects Of Imbruvica 140mg Capsule

Side Effects of Imbruvica 140mg Capsule

Like all medications, Imbruvica 140mg Capsule may cause side effects. However, not everyone will experience them.

Serious Side Effects (Seek immediate medical attention):

  • Severe bleeding
  • Persistent infections
  • Irregular heartbeat or chest discomfort
  • High blood pressure
  • Sudden weakness or numbness
  • Tumor lysis syndrome
  • Allergic reactions
  • Secondary cancers (rare)

Common Side Effects (Usually mild and temporary):

    Nausea, vomiting, diarrhea

    Tiredness and dizziness

    Muscle or bone pain

    Rash or bruising

    Mouth sores

    Fever or chills

    Cough or breathlessness

    Swelling in ankles or feet

    Constipation


Dosage Of Imbruvica 140mg Capsule

Take Imbruvica exactly as prescribed by your doctor, swallowing the capsule whole at the same time each day without opening, crushing, or chewing it. Drink plenty of fluids to stay hydrated. If you miss a dose, take it as soon as you remember on the same day, but skip it if it’s almost time for your next dose—never take a double dose.


Safety Advice for Imbruvica 140mg Capsule

Breast Feeding

Breast Feeding

Unsafe

This medicine should not be used while breastfeeding. To ensure infant safety, avoid breastfeeding during treatment and for one week after completing therapy.

Breast Feeding

Alcohol

Consult Your Doctor

There is limited information on alcohol interactions with Imbruvica. Because alcohol may increase certain side effects or strain the liver, it is best to speak with your doctor before consuming it.

Breast Feeding

Lungs

Safe

Inform your doctor if you have any history of lung disease. Rarely, Imbruvica may cause interstitial lung disease, so report symptoms like persistent cough or breathing difficulty immediately.

Breast Feeding

Driving

Unsafe

Imbruvica may cause dizziness, fatigue, or light-headedness. If you experience these symptoms, avoid driving or operating machinery for your safety.

Breast Feeding

Pregnancy

Unsafe

Imbruvica is unsafe to use during pregnancy, as it can harm the developing baby. Patients who can become pregnant should use reliable contraception throughout treatment and for at least one month after the last dose.

Storage Advice Of Imbruvica 140mg Capsule

  • Store at 20°C–25°C (room temperature).
  • Keep the Capsules away from light and moisture.
  • Store out of reach of children and pets.
  • Expert Tips

  • Take Imbruvica 140mg Capsule exactly as prescribed, at the same time each day. Do not stop without consulting your doctor.
  • Report signs like unusual bruising, bleeding, diarrhea, or fatigue early to your healthcare provider.
  • Regular blood tests are important to check how your body is responding to treatment.
  • Stay hydrated, eat balanced meals, and get proper rest to help your body manage therapy effectively.

  • FAQs about Imbruvica 140mg Capsule

    Q1. What is Imbruvica 140mg Capsule used for?

    Imbruvica 140mg Capsule is used to treat several blood cancers, including CLL, SLL, MCL, WM, and MZL. It is also prescribed for chronic graft-versus-host disease (cGvHD) when other treatments have not worked.

    Q2.How long does it take for Imbruvica to start working?

    The response time varies by patient and condition. Some people may notice improvements within weeks, while others may take several months. Your doctor will monitor your progress through regular checkups and blood tests.

    Q3. 3. Can I take Imbruvica with my other medicines?

    Imbruvica can interact with many medications, especially those affecting the CYP3A enzyme. Always inform your doctor about all prescription drugs, supplements, or herbal products you are taking.

    Q4. What foods should I avoid while taking Imbruvica?

    Avoid grapefruit, grapefruit juice, and Seville oranges, as they can increase the drug level in your bloodstream and raise the risk of side effects.

    Q5. What should I do if I experience severe side effects?

    If you develop symptoms like unusual bleeding, severe infection, chest pain, breathing problems, or irregular heartbeat, seek medical help immediately and inform your doctor right away.

    Key Fact Box

    Active ingredient Ibrutinib
    Pharmacologic class BTK inhibitor
    Medication category ANTI NEOPLASTICS
    Dosage forms Capsule

    Medical Advisory

      The information on the Phoenix Pharmex website is shared for educational purposes only and is not a substitute for professional medical advice or treatment. Always consult a doctor for any health-related questions. Please avoid self diagnosis or delaying medical care based on this content. Our mission is to support informed decisions not replace professional medical guidance.

    DOSAGE

    Frequently Asked Questions

    Azadine 100mg Injection contains Azacitidine which belongs to the group of medicines called Anticancer agents. It is used in adults to treat all sub-types of myelodysplastic syndromes (MDS; group of cancers associated with blood and bone marrow) and certain types of blood cancers known as Chronic myelomonocytic leukemia (CMML) and acute myeloid leukemia (AML).

    Azadine 100mg Injection is typically used in adults who cannot undergo stem cell transplantation. It may be also used to treat other conditions, as determined by the doctor.

    Azadine Injection is given as an injection under the medical supervision of a doctor. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised.

    You must inform your doctor before taking any vaccination while on treatment with this medicine. Regular blood tests are required to check your blood cells along with the heart, liver, and kidney.

    Before taking it, tell your doctor if you have liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using.

    MEDICINAL USE OF AZADINE 100MG INJECTION

    Azadine 100mg Injection is an anticancer medication. It works by blocking the actions of certain enzymes (DNA/RNA methyltransferase) within the cancer cells that is required for the cells to grow and multiply. It also reduces the production of new genetic material (RNA and DNA) within the cells. As a result, it prevents abnormal cell division within the body, slows down the growth of cancer cells and helps the bone marrow to produce normal blood cells.

    It is used to treat:

    • All sub-types of myelodysplastic syndromes (MDS; group of cancers associated with blood and bone marrow)
    • Chronic myelomonocytic leukemia (CMML; blood cancer of monocytes)
    • Acute myeloid leukemia (AML; blood cancer of WBC)
    SIDE EFFECTS OF AZADINE 100MG INJECTION

    Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.

    • Low RBC count causing anemia, tiredness and pale skin
    • Increased infections, lung infections (pneumonia), fever and chills
    • Increased bleeding tendency due to low blood platelet counts
    • Nausea, vomiting
    • Diarrhea, constipation, loss of appetite, stomach pain
    • Tiredness, weakness
    • Injection site reactions (such as pain, redness and swelling or lump formation)
    • Joint pain, muscle pain, skin rashes with redness and itching
    • Sore nose and throat, cold sores, sinnusitis
    • Headache, dizziness
    • Trouble sleeping (insomnia)
    • Nosebleeds, bleeding gums
    • Weight loss
    • Urinary tract infections
    • Ulcers of mouth or tongue
    • High or low blood pressure
    • Anxiety, confusion
    • Hair loss, dehydration
    • Oral fungal infection
    • Sleepiness
    • Fluid around the lungs or heart
    DOSAGE OF AZADINE 100MG INJECTION
    • The dose of Azacitidine is determined by the patient's height, weight, and general condition. It is given under the skin of your thigh, stomach, or upper arm.
    • Minimum of 4 to 6 cycles; may continue treatment if the patient continues to benefit.
    • Since Azadine 100 mg Injection is administered in the hospital or clinical setting by a qualified health care professional, the likelihood of a missed dose is very low.
    • Since Azadine 100 mg Injection is administered in the hospital or clinical setting by a qualified healthcare professional, the likelihood of an overdose is very low. However, emergency medical treatment will be initiated by the doctor if an overdose is suspected.

    Ques 1: What is the use of AZADINE 100MG INJECTION?

    Ans :AZADINE 100MG INJECTION is used in adults to treat all sub-types of myelodysplastic syndromes (MDS; group of cancers associated with blood and bone marrow) and certain types of blood cancers known as Chronic myelomonocytic leukemia (CMML) and acute myeloid leukemia (AML).

    Ques 2: How does AZADINE 100MG INJECTION works?

    Ans :AZADINE 100MG INJECTION is an anticancer medication. It works by blocking the actions of certain enzymes (DNA/RNA methyltransferase) within the cancer cells that is required for the cells to grow and multiply. It also reduces the production of new genetic material (RNA and DNA) within the cells. As a result, it prevents abnormal cell division within the body, slows down the growth of cancer cells and helps the bone marrow to produce normal blood cells.

    Ques 3: Can I take AZADINE 100MG INJECTION during breastfeeding?

    Ans :No. AZADINE 100MG INJECTION is not recommended for use in breast-feeding women. Therefore, inform your doctor before receiving it.

    Ques 4: Can AZADINE 100MG INJECTION increase the risk of infections?

    Ans :AZADINE 100MG INJECTION may cause a drop in the number of white blood cells in the body and may weaken your immune system. As a result, you may be at a greater risk of getting infected while receiving AZADINE 100MG INJECTION. To avoid this, your doctor will regular monitor your blood counts as a precaution. However, inform your doctor if you experience any signs of infection such as fever.

    Ques 5: Can the use of AZADINE 100MG INJECTION make me feel tired?

    Ans :Yes. AZADINE 100MG INJECTION may make you feel tired easily. This is because, it reduces the levels of red blood cells in your blood and may make you anemic. Consult your doctor if you experience tiredness after receiving AZADINE 100MG INJECTION. Tiredness can also occur if you have any pre-existing disease conditions such as liver or kidney impairment while receiving this medicine.

    Ques 6: Can I drive a car after receiving AZADINE 100MG INJECTION?

    Ans :AZADINE 100MG INJECTION may make you feel tired or weak. Therefore, do not drive or operate any heavy tools or machines if your ability is affected by AZADINE 100MG INJECTION.

    Ques 7: How AZADINE 100MG INJECTION is administered?

    Ans :AZADINE 100MG INJECTION will be given to you only by a doctor or a nurse beneath the skin (subcutaneously) of thighs, arms or abdomen.

    Ques 8: How to control nausea caused due to AZADINE 100MG INJECTION?

    Ans :Generally, anticancer medicines are associated with uncontrollable nausea and vomiting. To avoid this, your doctor would prescribe a suitable medicine to control them along with AZADINE 100MG INJECTION. If not, consult your doctor for a suitable anti-emetic medicine. Do not self-treat nausea.

    Overview Of Imbruvica 140mg Capsule

    Imbruvica 140mg Capsule contains Ibrutinib, a targeted cancer therapy used to treat several types of blood cancers. It is prescribed for mantle cell lymphoma (MCL), chronic lymphocytic leukemia (CLL), small lymphocytic lymphoma (SLL), Waldenström’s macroglobulinemia (WM), and marginal zone lymphoma (MZL). It is also effective in managing chronic graft-versus-host disease (cGvHD) when previous treatments have not worked.

    Imbruvica works by blocking abnormal cancer cell growth and helping restore healthy immune function. Because of its targeted mechanism, it offers a more precise and convenient oral treatment option compared to traditional chemotherapy.


    Usage Of Imbruvica 140mg Capsule

    Imbruvica 140mg Capsule is used to treat the following conditions:

    1. Treat Mantle Cell Lymphoma (MCL)

    2. Manage Chronic Lymphocytic Leukemia (CLL)

    3. Treat Small Lymphocytic Lymphoma (SLL)

    4. Treat Waldenström’s Macroglobulinemia (WM)

    5. Manage Marginal Zone Lymphoma (MZL)

    6. Treat Chronic Graft vs Host Disease (cGvHD) after failure of systemic therapy

    How Imbruvica 140mg Capsule Works

    Imbruvica (Ibrutinib) is a targeted Bruton’s Tyrosine Kinase (BTK) inhibitor that blocks key signaling pathways cancer cells rely on to grow and survive. By interrupting these signals, it slows disease progression, promotes programmed cell death (apoptosis), and helps reduce overall tumor burden. Its precise action on abnormal cells allows for effective, long-term disease control through convenient oral therapy.


    Side Effects Of Imbruvica 140mg Capsule

    Side Effects of Imbruvica 140mg Capsule

    Like all medications, Imbruvica 140mg Capsule may cause side effects. However, not everyone will experience them.

    Serious Side Effects (Seek immediate medical attention):

    • Severe bleeding
    • Persistent infections
    • Irregular heartbeat or chest discomfort
    • High blood pressure
    • Sudden weakness or numbness
    • Tumor lysis syndrome
    • Allergic reactions
    • Secondary cancers (rare)

    Common Side Effects (Usually mild and temporary):

      Nausea, vomiting, diarrhea

      Tiredness and dizziness

      Muscle or bone pain

      Rash or bruising

      Mouth sores

      Fever or chills

      Cough or breathlessness

      Swelling in ankles or feet

      Constipation


    Dosage Of Imbruvica 140mg Capsule

    Take Imbruvica exactly as prescribed by your doctor, swallowing the capsule whole at the same time each day without opening, crushing, or chewing it. Drink plenty of fluids to stay hydrated. If you miss a dose, take it as soon as you remember on the same day, but skip it if it’s almost time for your next dose—never take a double dose.


    Safety Advice for Imbruvica 140mg Capsule

    Breast Feeding

    Breast Feeding

    Unsafe

    This medicine should not be used while breastfeeding. To ensure infant safety, avoid breastfeeding during treatment and for one week after completing therapy.

    Breast Feeding

    Alcohol

    Consult Your Doctor

    There is limited information on alcohol interactions with Imbruvica. Because alcohol may increase certain side effects or strain the liver, it is best to speak with your doctor before consuming it.

    Breast Feeding

    Lungs

    Safe

    Inform your doctor if you have any history of lung disease. Rarely, Imbruvica may cause interstitial lung disease, so report symptoms like persistent cough or breathing difficulty immediately.

    Breast Feeding

    Driving

    Unsafe

    Imbruvica may cause dizziness, fatigue, or light-headedness. If you experience these symptoms, avoid driving or operating machinery for your safety.

    Breast Feeding

    Pregnancy

    Unsafe

    Imbruvica is unsafe to use during pregnancy, as it can harm the developing baby. Patients who can become pregnant should use reliable contraception throughout treatment and for at least one month after the last dose.

    Storage Advice Of Imbruvica 140mg Capsule

  • Store at 20°C–25°C (room temperature).
  • Keep the Capsules away from light and moisture.
  • Store out of reach of children and pets.
  • Expert Tips

  • Take Imbruvica 140mg Capsule exactly as prescribed, at the same time each day. Do not stop without consulting your doctor.
  • Report signs like unusual bruising, bleeding, diarrhea, or fatigue early to your healthcare provider.
  • Regular blood tests are important to check how your body is responding to treatment.
  • Stay hydrated, eat balanced meals, and get proper rest to help your body manage therapy effectively.

  • FAQs about Imbruvica 140mg Capsule

    Q1. What is Imbruvica 140mg Capsule used for?

    Imbruvica 140mg Capsule is used to treat several blood cancers, including CLL, SLL, MCL, WM, and MZL. It is also prescribed for chronic graft-versus-host disease (cGvHD) when other treatments have not worked.

    Q2.How long does it take for Imbruvica to start working?

    The response time varies by patient and condition. Some people may notice improvements within weeks, while others may take several months. Your doctor will monitor your progress through regular checkups and blood tests.

    Q3. 3. Can I take Imbruvica with my other medicines?

    Imbruvica can interact with many medications, especially those affecting the CYP3A enzyme. Always inform your doctor about all prescription drugs, supplements, or herbal products you are taking.

    Q4. What foods should I avoid while taking Imbruvica?

    Avoid grapefruit, grapefruit juice, and Seville oranges, as they can increase the drug level in your bloodstream and raise the risk of side effects.

    Q5. What should I do if I experience severe side effects?

    If you develop symptoms like unusual bleeding, severe infection, chest pain, breathing problems, or irregular heartbeat, seek medical help immediately and inform your doctor right away.

    Key Fact Box

    Active ingredient Ibrutinib
    Pharmacologic class BTK inhibitor
    Medication category ANTI NEOPLASTICS
    Dosage forms Capsule

    Medical Advisory

      The information on the Phoenix Pharmex website is shared for educational purposes only and is not a substitute for professional medical advice or treatment. Always consult a doctor for any health-related questions. Please avoid self diagnosis or delaying medical care based on this content. Our mission is to support informed decisions not replace professional medical guidance.

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