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Opdyta 40mg Injection

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Cold Chain
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Salt Composition

Manufacturer

BRISTOL MYERS SQUIBB

Origin of Medicine

United States of America

₹39000.00

    MRP:₹43780.00
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Overview & Usage

Overview Of Opdyta 40mg Injection

Opdyta 40mg Injection contains Nivolumab, an immunotherapy medicine used to treat several types of cancer, including cancer of the skin, lungs, kidneys, bladder, lymph nodes, esophagus, and urinary tract. It is often recommended when the cancer has returned or continued to grow despite earlier treatments such as surgery, radiation, or chemotherapy. Opdyta strengthens the immune system so it can better recognize and destroy cancer cells.


Usage Of Opdyta 40mg Injection

Opdyta 40mg Injection is used in adults to treat:

1. Advanced or recurrent skin cancer

2. Non-small cell lung cancer

3. Advanced kidney cancer

4. Hodgkin’s lymphoma

4. Bladder and urinary tract cancer

4. Esophageal cancer

How Opdyta 40mg Injection Works

Nivolumab works by blocking the PD-1 pathway, a mechanism cancer cells use to hide from the immune system. By stopping this interaction, Opdyta 40mg allows immune cells to recognize and attack cancer cells more effectively. This can slow or stop tumor growth and, in some cases, lead to long-lasting remission even after treatment ends. However, because it boosts immune activity, it may worsen autoimmune conditions or trigger inflammation in vital organs.


Side Effects Of Opdyta 40mg Injection

Side Effects of Opdyta 40mg Injection

Like all medications, Opdyta 40mg Injection may cause side effects. However, not everyone will experience them.

Serious Side Effects (Seek immediate medical attention):

  • Pneumonitis (lung inflammation)
  • Colitis (bowel inflammation)
  • Hepatitis (liver inflammation)
  • Thyroid disorders (hypo/hyperthyroidism)
  • Adrenal gland problems
  • Severe allergic reactions
  • Infusion-related reactions
  • Confusion or seizures
  • Eye inflammation
  • Note: Always consult your doctor if you experience any unusual symptoms or if common side effects become severe.

Common Side Effects (Usually mild and temporary):

    These are usually mild to moderate and may improve as your body adjusts to the treatment:

  • Nausea or vomiting
  • Fatigue or tiredness
  • Diarrhea or constipation
  • Headache
  • Loss of appetite
  • Hair thinning or hair loss
  • Joint pain

Dosage Of Opdyta 40mg Injection

Opdyta 40mg Injection is given only by a trained healthcare professional as an intravenous infusion in a hospital or clinic. The treatment schedule depends on your cancer type and how your body responds. You will be monitored during the infusion for any reactions. If you miss an appointment, inform your doctor do not make up the dose on your own.


Safety Advice for Opdyta 40mg Injection

Breast Feeding

Breast Feeding

Unsafe

It is not known whether Nivolumab passes into breast milk. Because it may potentially affect the immune system of a nursing infant, mothers should avoid breastfeeding during treatment and for some time after the final dose unless advised otherwise by a doctor.

Breast Feeding

Alcohol

Consult Your Doctor

Consuming alcohol while taking Opdyta 40mg may worsen side effects such as dizziness, tiredness, nausea, or liver strain. It’s best to limit or avoid alcohol to prevent complications and to help your body tolerate the treatment better.

Breast Feeding

Liver

Unsafe

Use with caution if you have existing liver problems. Opdyta 40mg Injection can sometimes trigger inflammation of the liver (hepatitis) , which may worsen pre-existing conditions. Your doctor may conduct regular blood tests and imaging scans to monitor organ function throughout treatment.

Breast Feeding

Driving

Unsafe

Avoid driving or operating heavy machinery if you feel dizzy, weak, unusually tired, or experience blurred vision after receiving Opdyta 40mg Injection. These symptoms can affect your alertness and reaction time.

Breast Feeding

Pregnancy

Unsafe

Opdyta 40mg Injection is not safe during pregnancy or breastfeeding. Use effective contraception during treatment and for at least 7 months after the last dose.

Storage Advice Of Opdyta 40mg Injection

  • Store in a refrigerator (2 - 8°C)
  • Do not freeze
  • Keep out of reach of children and pets
  • Expert Tips

  • Receive Opdyta 40mg Injection exactly as prescribed by your oncologist for effective results.
  • Routine monitoring helps track your progress and manage any treatment-related side effects.
  • Inform your doctor if you notice fatigue, cough, skin rash, or breathing problems.
  • Balanced nutrition, proper hydration, and adequate rest can support your body during treatment.

  • FAQs about Opdyta 40mg Injection

    Q1. Can Opdyta 40mg Injection cause skin problems?

    Yes. Skin-related side effects like rashes, redness, itching, dryness, or even blistering may occur because Opdyta 40mg Injection activates your immune system, which can sometimes react against the skin. Mild reactions are common, but if you develop severe rashes, peeling skin, or painful blisters, contact your doctor immediately as this may require medical treatment.

    Q2. Does Opdyta 40mg Injection affect fertility?

    There is limited long-term data, but Opdyta 40mg Injection may affect fertility in both men and women due to its impact on hormones and the immune system. If you plan to have children in the future, discuss fertility preservation options (such as sperm or egg storage) with your doctor before beginning treatment.

    Q3. Can Opdyta 40mg Injection cause diabetes?

    Although rare, Opdyta 40mg Injection can sometimes affect the pancreas and lead to increased blood sugar levels or trigger new-onset diabetes. Symptoms may include excessive thirst, frequent urination, or unusual tiredness. Regular blood sugar monitoring is recommended throughout treatment to detect any changes early.

    Q4. Is Opdyta 40mg Injection safe for children?

    Opdyta 40mg Injection is not approved for use in children, except under special circumstances such as participation in clinical trials. Its safety and effectiveness in pediatric patients have not been fully established, so treatment should only be considered under strict medical supervision.

    Q5. How is Opdyta 40mg Injection different from chemotherapy?

    Opdyta 40mg Injection is an immunotherapy, meaning it strengthens your immune system to recognize and attack cancer cells. Chemotherapy, on the other hand, directly kills fast-growing cells. As a result, Opdyta 40mg Injection generally has different side effects and may be better tolerated, though immune-related reactions can still occur. Treatment choice depends on your cancer type and overall health.

    Q6. How often will I be monitored during treatment?

    During Opdyta 40mg Injection therapy, you will have regular medical evaluations, including blood tests, imaging scans (such as CT or MRI), and physical examinations. This helps your doctor track how well the treatment is working and quickly identify any immune-related side effects. Monitoring schedules may vary depending on your condition and treatment response.

    Key Fact Box

    Active ingredient Nivolumab
    Pharmacologic class Monoclonal antibody (mAb)
    Medication category ANTI NEOPLASTICS
    Dosage forms Injection

    Medical Advisory

      The information on the Phoenix Pharmex website is shared for educational purposes only and is not a substitute for professional medical advice or treatment. Always consult a doctor for any health-related questions. Please avoid self diagnosis or delaying medical care based on this content. Our mission is to support informed decisions not replace professional medical guidance.

    DOSAGE

    Frequently Asked Questions

    Azadine 100mg Injection contains Azacitidine which belongs to the group of medicines called Anticancer agents. It is used in adults to treat all sub-types of myelodysplastic syndromes (MDS; group of cancers associated with blood and bone marrow) and certain types of blood cancers known as Chronic myelomonocytic leukemia (CMML) and acute myeloid leukemia (AML).

    Azadine 100mg Injection is typically used in adults who cannot undergo stem cell transplantation. It may be also used to treat other conditions, as determined by the doctor.

    Azadine Injection is given as an injection under the medical supervision of a doctor. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised.

    You must inform your doctor before taking any vaccination while on treatment with this medicine. Regular blood tests are required to check your blood cells along with the heart, liver, and kidney.

    Before taking it, tell your doctor if you have liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using.

    MEDICINAL USE OF AZADINE 100MG INJECTION

    Azadine 100mg Injection is an anticancer medication. It works by blocking the actions of certain enzymes (DNA/RNA methyltransferase) within the cancer cells that is required for the cells to grow and multiply. It also reduces the production of new genetic material (RNA and DNA) within the cells. As a result, it prevents abnormal cell division within the body, slows down the growth of cancer cells and helps the bone marrow to produce normal blood cells.

    It is used to treat:

    • All sub-types of myelodysplastic syndromes (MDS; group of cancers associated with blood and bone marrow)
    • Chronic myelomonocytic leukemia (CMML; blood cancer of monocytes)
    • Acute myeloid leukemia (AML; blood cancer of WBC)
    SIDE EFFECTS OF AZADINE 100MG INJECTION

    Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.

    • Low RBC count causing anemia, tiredness and pale skin
    • Increased infections, lung infections (pneumonia), fever and chills
    • Increased bleeding tendency due to low blood platelet counts
    • Nausea, vomiting
    • Diarrhea, constipation, loss of appetite, stomach pain
    • Tiredness, weakness
    • Injection site reactions (such as pain, redness and swelling or lump formation)
    • Joint pain, muscle pain, skin rashes with redness and itching
    • Sore nose and throat, cold sores, sinnusitis
    • Headache, dizziness
    • Trouble sleeping (insomnia)
    • Nosebleeds, bleeding gums
    • Weight loss
    • Urinary tract infections
    • Ulcers of mouth or tongue
    • High or low blood pressure
    • Anxiety, confusion
    • Hair loss, dehydration
    • Oral fungal infection
    • Sleepiness
    • Fluid around the lungs or heart
    DOSAGE OF AZADINE 100MG INJECTION
    • The dose of Azacitidine is determined by the patient's height, weight, and general condition. It is given under the skin of your thigh, stomach, or upper arm.
    • Minimum of 4 to 6 cycles; may continue treatment if the patient continues to benefit.
    • Since Azadine 100 mg Injection is administered in the hospital or clinical setting by a qualified health care professional, the likelihood of a missed dose is very low.
    • Since Azadine 100 mg Injection is administered in the hospital or clinical setting by a qualified healthcare professional, the likelihood of an overdose is very low. However, emergency medical treatment will be initiated by the doctor if an overdose is suspected.

    Ques 1: What is the use of AZADINE 100MG INJECTION?

    Ans :AZADINE 100MG INJECTION is used in adults to treat all sub-types of myelodysplastic syndromes (MDS; group of cancers associated with blood and bone marrow) and certain types of blood cancers known as Chronic myelomonocytic leukemia (CMML) and acute myeloid leukemia (AML).

    Ques 2: How does AZADINE 100MG INJECTION works?

    Ans :AZADINE 100MG INJECTION is an anticancer medication. It works by blocking the actions of certain enzymes (DNA/RNA methyltransferase) within the cancer cells that is required for the cells to grow and multiply. It also reduces the production of new genetic material (RNA and DNA) within the cells. As a result, it prevents abnormal cell division within the body, slows down the growth of cancer cells and helps the bone marrow to produce normal blood cells.

    Ques 3: Can I take AZADINE 100MG INJECTION during breastfeeding?

    Ans :No. AZADINE 100MG INJECTION is not recommended for use in breast-feeding women. Therefore, inform your doctor before receiving it.

    Ques 4: Can AZADINE 100MG INJECTION increase the risk of infections?

    Ans :AZADINE 100MG INJECTION may cause a drop in the number of white blood cells in the body and may weaken your immune system. As a result, you may be at a greater risk of getting infected while receiving AZADINE 100MG INJECTION. To avoid this, your doctor will regular monitor your blood counts as a precaution. However, inform your doctor if you experience any signs of infection such as fever.

    Ques 5: Can the use of AZADINE 100MG INJECTION make me feel tired?

    Ans :Yes. AZADINE 100MG INJECTION may make you feel tired easily. This is because, it reduces the levels of red blood cells in your blood and may make you anemic. Consult your doctor if you experience tiredness after receiving AZADINE 100MG INJECTION. Tiredness can also occur if you have any pre-existing disease conditions such as liver or kidney impairment while receiving this medicine.

    Ques 6: Can I drive a car after receiving AZADINE 100MG INJECTION?

    Ans :AZADINE 100MG INJECTION may make you feel tired or weak. Therefore, do not drive or operate any heavy tools or machines if your ability is affected by AZADINE 100MG INJECTION.

    Ques 7: How AZADINE 100MG INJECTION is administered?

    Ans :AZADINE 100MG INJECTION will be given to you only by a doctor or a nurse beneath the skin (subcutaneously) of thighs, arms or abdomen.

    Ques 8: How to control nausea caused due to AZADINE 100MG INJECTION?

    Ans :Generally, anticancer medicines are associated with uncontrollable nausea and vomiting. To avoid this, your doctor would prescribe a suitable medicine to control them along with AZADINE 100MG INJECTION. If not, consult your doctor for a suitable anti-emetic medicine. Do not self-treat nausea.

    Overview Of Opdyta 40mg Injection

    Opdyta 40mg Injection contains Nivolumab, an immunotherapy medicine used to treat several types of cancer, including cancer of the skin, lungs, kidneys, bladder, lymph nodes, esophagus, and urinary tract. It is often recommended when the cancer has returned or continued to grow despite earlier treatments such as surgery, radiation, or chemotherapy. Opdyta strengthens the immune system so it can better recognize and destroy cancer cells.


    Usage Of Opdyta 40mg Injection

    Opdyta 40mg Injection is used in adults to treat:

    1. Advanced or recurrent skin cancer

    2. Non-small cell lung cancer

    3. Advanced kidney cancer

    4. Hodgkin’s lymphoma

    4. Bladder and urinary tract cancer

    4. Esophageal cancer

    How Opdyta 40mg Injection Works

    Nivolumab works by blocking the PD-1 pathway, a mechanism cancer cells use to hide from the immune system. By stopping this interaction, Opdyta 40mg allows immune cells to recognize and attack cancer cells more effectively. This can slow or stop tumor growth and, in some cases, lead to long-lasting remission even after treatment ends. However, because it boosts immune activity, it may worsen autoimmune conditions or trigger inflammation in vital organs.


    Side Effects Of Opdyta 40mg Injection

    Side Effects of Opdyta 40mg Injection

    Like all medications, Opdyta 40mg Injection may cause side effects. However, not everyone will experience them.

    Serious Side Effects (Seek immediate medical attention):

    • Pneumonitis (lung inflammation)
    • Colitis (bowel inflammation)
    • Hepatitis (liver inflammation)
    • Thyroid disorders (hypo/hyperthyroidism)
    • Adrenal gland problems
    • Severe allergic reactions
    • Infusion-related reactions
    • Confusion or seizures
    • Eye inflammation
    • Note: Always consult your doctor if you experience any unusual symptoms or if common side effects become severe.

    Common Side Effects (Usually mild and temporary):

      These are usually mild to moderate and may improve as your body adjusts to the treatment:

    • Nausea or vomiting
    • Fatigue or tiredness
    • Diarrhea or constipation
    • Headache
    • Loss of appetite
    • Hair thinning or hair loss
    • Joint pain

    Dosage Of Opdyta 40mg Injection

    Opdyta 40mg Injection is given only by a trained healthcare professional as an intravenous infusion in a hospital or clinic. The treatment schedule depends on your cancer type and how your body responds. You will be monitored during the infusion for any reactions. If you miss an appointment, inform your doctor do not make up the dose on your own.


    Safety Advice for Opdyta 40mg Injection

    Breast Feeding

    Breast Feeding

    Unsafe

    It is not known whether Nivolumab passes into breast milk. Because it may potentially affect the immune system of a nursing infant, mothers should avoid breastfeeding during treatment and for some time after the final dose unless advised otherwise by a doctor.

    Breast Feeding

    Alcohol

    Consult Your Doctor

    Consuming alcohol while taking Opdyta 40mg may worsen side effects such as dizziness, tiredness, nausea, or liver strain. It’s best to limit or avoid alcohol to prevent complications and to help your body tolerate the treatment better.

    Breast Feeding

    Liver

    Unsafe

    Use with caution if you have existing liver problems. Opdyta 40mg Injection can sometimes trigger inflammation of the liver (hepatitis) , which may worsen pre-existing conditions. Your doctor may conduct regular blood tests and imaging scans to monitor organ function throughout treatment.

    Breast Feeding

    Driving

    Unsafe

    Avoid driving or operating heavy machinery if you feel dizzy, weak, unusually tired, or experience blurred vision after receiving Opdyta 40mg Injection. These symptoms can affect your alertness and reaction time.

    Breast Feeding

    Pregnancy

    Unsafe

    Opdyta 40mg Injection is not safe during pregnancy or breastfeeding. Use effective contraception during treatment and for at least 7 months after the last dose.

    Storage Advice Of Opdyta 40mg Injection

  • Store in a refrigerator (2 - 8°C)
  • Do not freeze
  • Keep out of reach of children and pets
  • Expert Tips

  • Receive Opdyta 40mg Injection exactly as prescribed by your oncologist for effective results.
  • Routine monitoring helps track your progress and manage any treatment-related side effects.
  • Inform your doctor if you notice fatigue, cough, skin rash, or breathing problems.
  • Balanced nutrition, proper hydration, and adequate rest can support your body during treatment.

  • FAQs about Opdyta 40mg Injection

    Q1. Can Opdyta 40mg Injection cause skin problems?

    Yes. Skin-related side effects like rashes, redness, itching, dryness, or even blistering may occur because Opdyta 40mg Injection activates your immune system, which can sometimes react against the skin. Mild reactions are common, but if you develop severe rashes, peeling skin, or painful blisters, contact your doctor immediately as this may require medical treatment.

    Q2. Does Opdyta 40mg Injection affect fertility?

    There is limited long-term data, but Opdyta 40mg Injection may affect fertility in both men and women due to its impact on hormones and the immune system. If you plan to have children in the future, discuss fertility preservation options (such as sperm or egg storage) with your doctor before beginning treatment.

    Q3. Can Opdyta 40mg Injection cause diabetes?

    Although rare, Opdyta 40mg Injection can sometimes affect the pancreas and lead to increased blood sugar levels or trigger new-onset diabetes. Symptoms may include excessive thirst, frequent urination, or unusual tiredness. Regular blood sugar monitoring is recommended throughout treatment to detect any changes early.

    Q4. Is Opdyta 40mg Injection safe for children?

    Opdyta 40mg Injection is not approved for use in children, except under special circumstances such as participation in clinical trials. Its safety and effectiveness in pediatric patients have not been fully established, so treatment should only be considered under strict medical supervision.

    Q5. How is Opdyta 40mg Injection different from chemotherapy?

    Opdyta 40mg Injection is an immunotherapy, meaning it strengthens your immune system to recognize and attack cancer cells. Chemotherapy, on the other hand, directly kills fast-growing cells. As a result, Opdyta 40mg Injection generally has different side effects and may be better tolerated, though immune-related reactions can still occur. Treatment choice depends on your cancer type and overall health.

    Q6. How often will I be monitored during treatment?

    During Opdyta 40mg Injection therapy, you will have regular medical evaluations, including blood tests, imaging scans (such as CT or MRI), and physical examinations. This helps your doctor track how well the treatment is working and quickly identify any immune-related side effects. Monitoring schedules may vary depending on your condition and treatment response.

    Key Fact Box

    Active ingredient Nivolumab
    Pharmacologic class Monoclonal antibody (mAb)
    Medication category ANTI NEOPLASTICS
    Dosage forms Injection

    Medical Advisory

      The information on the Phoenix Pharmex website is shared for educational purposes only and is not a substitute for professional medical advice or treatment. Always consult a doctor for any health-related questions. Please avoid self diagnosis or delaying medical care based on this content. Our mission is to support informed decisions not replace professional medical guidance.

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