Azadine 150mg Injection contains azacitidine, an anticancer medicine used in adults to treat blood-related cancers such as myelodysplastic syndromes (MDS), chronic myelomonocytic leukaemia (CMML), and certain cases of acute myeloid leukaemia (AML). These conditions affect the bone marrow and lead to abnormal production of white blood cells, causing symptoms like frequent infections, fatigue, fever, and easy bruising or bleeding. Azadine 150mg Injection is generally prescribed for patients who are not eligible for stem cell transplantation and helps slow disease progression by targeting abnormal bone marrow cells.

Before starting Azadine 150mg Injection treatment, patients should inform their doctor about any existing lung, liver, kidney, or heart conditions. This injection is not recommended during pregnancy or breastfeeding, and effective contraception is advised for both men and women during therapy. Common side effects may include nausea, vomiting, fatigue, diarrhea, constipation, loss of appetite, weakness, infections, and injection-site reactions such as pain or redness. Other possible effects include mouth ulcers, headache, dizziness, hair loss, and weight loss. If side effects persist or worsen, medical advice should be sought promptly.

Azadine 150mg Injection is an effective chemotherapy drug used in the treatment of blood cancers such as myelodysplastic syndromes and leukemia. It works through a dual mechanism of action at lower doses, azacitidine inhibits the DNA methyltransferase enzyme, leading to DNA hypomethylation that reactivates normal genes and helps slow the growth of cancer cells. At higher doses, it incorporates into RNA and DNA, disrupting their function and destroying rapidly dividing abnormal blood cells in the bone marrow, while having minimal impact on healthy, non-dividing cells.

Side Effects of Azadine 150mg Injection

Like all medications, Azadine 150mg Injection may cause side effects. However, not everyone will experience them.

Serious Side Effects (Seek immediate medical attention):

• Increased risk of infections (due to low white blood cells)
• Fever, chills, or persistent sore throat (signs of infection)
• Easy bruising or excessive bleeding (due to low platelet count)
• Severe allergic reactions – rash, itching, swelling, difficulty breathing (rare)
• Very low blood cell counts (anemia, neutropenia, thrombocytopenia)
• Signs of organ toxicity (e.g., yellowing of eyes/skin, dark urine – indicating liver issues)

Common Side Effects (Usually mild and temporary):

• Fatigue or tiredness
• Nausea and vomiting
• Loss of appetite
• Abdominal (stomach) pain
• General weakness
• Pain, redness, or swelling at the injection site
• Headache
• Dizziness
• Trouble sleeping (insomnia)
• Sore throat or cold sores
• Mouth or tongue ulcers
• Weight loss
• Hair loss

The dosage of Azadine 150mg Injection is determined by a doctor based on the patient’s body surface area, medical condition, and response to treatment. It is administered by a healthcare professional either under the skin (subcutaneously) or into a vein (intravenously).

Breast Feeding

Unsafe

Azadine 150mg Injection is not safe while breastfeeding, as it may pass into breast milk and harm the baby.

Alcohol

Consult Your Doctor

You need to tell your physician if you have any liver disorders before starting Azadine 150mg Injection as it requires dosage adjustment for severe liver impairment.

Lungs

Unsafe

Talk to your doctor if you have any lung conditions before starting treatment with Azadine 150mg Injection.

Driving

Unsafe

Azadine 150mg Injection may cause dizziness or fatigue. Avoid driving or using heavy machinery if you feel unwell.

Pregnancy

Unsafe

Azadine 150mg Injection should not be used during pregnancy as it may harm the baby. In very serious cases, your doctor might still give it if the benefits are greater than the risks. Always talk to your doctor first.

Azadine 150mg Injection is used to treat certain types of blood and bone marrow cancers in adults, including myelodysplastic syndromes (MDS), chronic myelomonocytic leukaemia (CMML), and acute myeloid leukaemia (AML).

Azadine 150mg Injection contains Azacitidine, which works by blocking abnormal DNA activity and killing rapidly growing cancer cells in the bone marrow. It helps restore normal blood cell production and slows disease progression.

Azadine 150mg Injection is given by injection, either under the skin (subcutaneously) or into a vein (intravenously), usually once daily for 7 days in a 28-day treatment cycle. It must be administered by a healthcare professional.

Common side effects include fatigue, nausea, vomiting, diarrhea, constipation, appetite loss, injection site reactions, mouth ulcers, and low blood counts, which may lead to infections or bleeding.

No. Azadine 150mg Injection is not recommended during pregnancy or breastfeeding. Effective birth control should be used during treatment. Men may consider sperm preservation before starting therapy.

Yes. Your doctor will monitor your blood counts, liver, and kidney function regularly to ensure the treatment is safe and effective.

You should inform your doctor about all the medicines you are taking. Some drugs may interact with Azadine, so medical supervision is important.

Treatment duration varies by individual. Most patients receive at least 6 cycles, but your doctor will decide based on how you respond to the treatment.

The information on the Phoenix Pharmex website is shared for educational purposes only and is not a substitute for professional medical advice or treatment. Always consult a doctor for any health-related questions. Please avoid self diagnosis or delaying medical care based on this content. Our mission is to support informed decisions not replace professional medical guidance.