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Xbira 500mg Tablet

Prescription Required
prescription

Salt Composition

Manufacturer

CIPLA LTD

Origin of Medicine

India

₹11000.00

    MRP:₹20625.00
Save ₹ 9625 (47%)
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Overview & Usage

Overview Of Xbira 500mg Tablet

Xbira 500mg Tablet contains Abiraterone, an androgen biosynthesis inhibitor used to treat advanced prostate cancer, particularly metastatic castration-resistant prostate cancer (mCRPC). It is prescribed when the cancer continues to grow despite treatments that lower testosterone levels. Abiraterone works by blocking the CYP17A1 enzyme, which reduces the production of androgens like testosterone that fuel prostate cancer growth, helping slow disease progression.

Lowering androgen levels may increase aldosterone, which can cause side effects such as high blood pressure, fluid retention, and low potassium levels. To reduce these risks, Xbira is usually taken along with prednisone. Patients should inform their doctor about any existing heart, liver, or kidney conditions, high blood pressure, or other medications they are taking, as Abiraterone may interact with certain drugs and requires careful medical monitoring.


Usage Of Xbira 500mg Tablet

1. Metastatic castration-resistant prostate cancer (mCRPC)

2. Metastatic high-risk castration-sensitive prostate cancer (mCSPC)

Abiraterone is usually taken along with a corticosteroid (like prednisone) to help reduce side effects and improve treatment outcomes.

How Xbira 500mg Tablet Works

Xbira 500mg Tablet contains Abiraterone acetate, a prodrug that converts into abiraterone, a selective CYP17 inhibitor used in the treatment of metastatic castration-resistant prostate cancer (mCRPC). It works by blocking the CYP17A1 enzyme responsible for producing androgens such as testosterone in the adrenal glands, testes, and tumor tissues, thereby reducing hormone levels that fuel prostate cancer growth. Because this strong hormone suppression may cause side effects like fluid retention and low potassium levels, Xbira is usually prescribed along with prednisone to improve safety and treatment effectiveness.


Side Effects Of Xbira 500mg Tablet

Side Effects of Xbira 500mg Tablet

Like all medications, Xbira 500mg Tablet may cause side effects. However, not everyone will experience them.

Serious Side Effects (Seek immediate medical attention):

  • Low potassium (hypokalemia): Muscle cramps, feeling faint
  • Heart symptoms: High blood pressure, chest pain, irregular heartbeat
  • Liver symptoms: Stomach pain, nausea, jaundice (yellow skin/eyes)
  • Severe infections such as sepsis (a life-threatening complication of infection)
  • Bone fractures
  • Blood in urine
  • Adrenal insufficiency (adrenal glands not producing enough hormones)
  • Lung irritation (allergic alveolitis)

Common Side Effects (Usually mild and temporary):

  • Swelling in legs or feet
  • Diarrhea, indigestion
  • Urinary tract infection (UTI)
  • Muscle weakness or pain
  • Rash

Dosage Of Xbira 500mg Tablet

The usual recommended dose of Xbira 500mg Tablet is 1000 mg once daily (4 tablets), taken on an empty stomach either 1 hour before or 2 hours after food with a glass of water. The exact dose should always be followed as prescribed by your doctor, especially if you have existing medical conditions. During treatment, regular blood tests may be advised to monitor liver and kidney function, blood counts, and lipid levels, helping ensure the medicine is safe and effective.


Safety Advice for Xbira 500mg Tablet

Breast Feeding

Breast Feeding

Unsafe

Xbira 500mg Tablet is not for use in women, especially during breastfeeding, as it can harm the baby.

Breast Feeding

Alcohol

Consult Your Doctor

Limit or avoid alcohol, as it may worsen liver related side effects.

Breast Feeding

Lungs

Unsafe

Inform your doctor about any lung problems before starting Xbira 500mg Tablet.

Breast Feeding

Driving

Unsafe

Xbira 500mg Tablet may cause dizziness, tiredness, or high blood pressure. Avoid driving or operating machines if you feel unwell.

Breast Feeding

Pregnancy

Unsafe

Xbira 500mg Tablet is not for use in women, especially during pregnancy, as it can harm the baby.

Storage Advice Of Xbira 500mg Tablet

  • Store at room temperature between 20°C to 25°
  • Keep out of reach of children and pets
  • Keep the container tightly closed when not in use.
  • Keep the tablets in the original packaging to protect them from moisture and light.
  • Expert Tips

  • Take Xbira 500mg Tablet (abiraterone acetate) exactly as prescribed by your doctor.
  • Always take the tablet on an empty stomach (at least 1 hour before or 2 hours after food) to avoid increased absorption and side effects.
  • Take it at the same time every day to maintain consistent drug levels in the body.
  • Patients with liver disease, heart conditions, or high blood pressure should use this medicine with caution.

  • FAQs about Xbira 500mg tablet?

    Q1. How should I take the Xbira 500mg tablet?

    Take Xbira 500mg exactly as your doctor prescribes. Swallow it on an empty stomach at least 2 hours after a meal, and do not eat anything for 1 hour after taking the tablet.

    Q2. Does Xbira 500mg Tablet interact with food or drinks?

    Yes, Xbira 500mg Tablet should be taken on an empty stomach. Eating before or after taking it can increase the drug’s absorption and raise the risk of side effects. Follow your doctor’s instructions carefully typically, no food for 2 hours before and 1 hour after taking the tablet. While it's unclear if alcohol directly interacts with abiraterone, both can affect liver function, so it's best to limit or avoid alcohol during treatment.

    Q3. Can Xbira 500mg tablet worsen liver disease?

    Yes, Xbira 500mg is not recommended for people with severe liver problems, as it can further impair liver function. Always inform your doctor about any existing liver conditions before starting this medicine.

    Q4. Can Xbira 500mg tablet cure prostate cancer?

    No, Xbira 500mg does not cure prostate cancer. It is used to manage and slow the progression of advanced or metastatic prostate cancer, especially when the cancer has spread beyond the prostate. It’s usually given with a corticosteroid to reduce side effects and is often used alongside androgen deprivation therapy (ADT) to lower testosterone levels, which helps control the disease.

    Q5. Does Xbira 500mg Tablet interact with other medicines?

    Xbira 500mg Tablet can interact with many medicines, so always inform your doctor about all prescription drugs, over-the-counter medicines, supplements, or vitamins you take. Certain medicines for seizures, tuberculosis, diabetes, mental health conditions, cough relief, and some cancer treatments may change how abiraterone works or increase side effects.

    Q6. What should I do if I miss a dose of Xbira 500mg Tablet?

    If you miss a dose, skip it and take your next dose at the regular scheduled time. Do not take a double dose to make up for the missed one. If you miss more than one dose, contact your doctor for further advice.

    Key Fact Box

    Active ingredient Abiraterone acetate
    Pharmacologic class Androgen Biosynthesis Inhibitors
    Medication category ANTI NEOPLASTICS
    Dosage forms Tablet

    Medical Advisory

      The information on the Phoenix Pharmex website is shared for educational purposes only and is not a substitute for professional medical advice or treatment. Always consult a doctor for any health-related questions. Please avoid self diagnosis or delaying medical care based on this content. Our mission is to support informed decisions not replace professional medical guidance.

    DOSAGE

    Frequently Asked Questions

    Azadine 100mg Injection contains Azacitidine which belongs to the group of medicines called Anticancer agents. It is used in adults to treat all sub-types of myelodysplastic syndromes (MDS; group of cancers associated with blood and bone marrow) and certain types of blood cancers known as Chronic myelomonocytic leukemia (CMML) and acute myeloid leukemia (AML).

    Azadine 100mg Injection is typically used in adults who cannot undergo stem cell transplantation. It may be also used to treat other conditions, as determined by the doctor.

    Azadine Injection is given as an injection under the medical supervision of a doctor. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised.

    You must inform your doctor before taking any vaccination while on treatment with this medicine. Regular blood tests are required to check your blood cells along with the heart, liver, and kidney.

    Before taking it, tell your doctor if you have liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using.

    MEDICINAL USE OF AZADINE 100MG INJECTION

    Azadine 100mg Injection is an anticancer medication. It works by blocking the actions of certain enzymes (DNA/RNA methyltransferase) within the cancer cells that is required for the cells to grow and multiply. It also reduces the production of new genetic material (RNA and DNA) within the cells. As a result, it prevents abnormal cell division within the body, slows down the growth of cancer cells and helps the bone marrow to produce normal blood cells.

    It is used to treat:

    • All sub-types of myelodysplastic syndromes (MDS; group of cancers associated with blood and bone marrow)
    • Chronic myelomonocytic leukemia (CMML; blood cancer of monocytes)
    • Acute myeloid leukemia (AML; blood cancer of WBC)
    SIDE EFFECTS OF AZADINE 100MG INJECTION

    Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.

    • Low RBC count causing anemia, tiredness and pale skin
    • Increased infections, lung infections (pneumonia), fever and chills
    • Increased bleeding tendency due to low blood platelet counts
    • Nausea, vomiting
    • Diarrhea, constipation, loss of appetite, stomach pain
    • Tiredness, weakness
    • Injection site reactions (such as pain, redness and swelling or lump formation)
    • Joint pain, muscle pain, skin rashes with redness and itching
    • Sore nose and throat, cold sores, sinnusitis
    • Headache, dizziness
    • Trouble sleeping (insomnia)
    • Nosebleeds, bleeding gums
    • Weight loss
    • Urinary tract infections
    • Ulcers of mouth or tongue
    • High or low blood pressure
    • Anxiety, confusion
    • Hair loss, dehydration
    • Oral fungal infection
    • Sleepiness
    • Fluid around the lungs or heart
    DOSAGE OF AZADINE 100MG INJECTION
    • The dose of Azacitidine is determined by the patient's height, weight, and general condition. It is given under the skin of your thigh, stomach, or upper arm.
    • Minimum of 4 to 6 cycles; may continue treatment if the patient continues to benefit.
    • Since Azadine 100 mg Injection is administered in the hospital or clinical setting by a qualified health care professional, the likelihood of a missed dose is very low.
    • Since Azadine 100 mg Injection is administered in the hospital or clinical setting by a qualified healthcare professional, the likelihood of an overdose is very low. However, emergency medical treatment will be initiated by the doctor if an overdose is suspected.

    Ques 1: What is the use of AZADINE 100MG INJECTION?

    Ans :AZADINE 100MG INJECTION is used in adults to treat all sub-types of myelodysplastic syndromes (MDS; group of cancers associated with blood and bone marrow) and certain types of blood cancers known as Chronic myelomonocytic leukemia (CMML) and acute myeloid leukemia (AML).

    Ques 2: How does AZADINE 100MG INJECTION works?

    Ans :AZADINE 100MG INJECTION is an anticancer medication. It works by blocking the actions of certain enzymes (DNA/RNA methyltransferase) within the cancer cells that is required for the cells to grow and multiply. It also reduces the production of new genetic material (RNA and DNA) within the cells. As a result, it prevents abnormal cell division within the body, slows down the growth of cancer cells and helps the bone marrow to produce normal blood cells.

    Ques 3: Can I take AZADINE 100MG INJECTION during breastfeeding?

    Ans :No. AZADINE 100MG INJECTION is not recommended for use in breast-feeding women. Therefore, inform your doctor before receiving it.

    Ques 4: Can AZADINE 100MG INJECTION increase the risk of infections?

    Ans :AZADINE 100MG INJECTION may cause a drop in the number of white blood cells in the body and may weaken your immune system. As a result, you may be at a greater risk of getting infected while receiving AZADINE 100MG INJECTION. To avoid this, your doctor will regular monitor your blood counts as a precaution. However, inform your doctor if you experience any signs of infection such as fever.

    Ques 5: Can the use of AZADINE 100MG INJECTION make me feel tired?

    Ans :Yes. AZADINE 100MG INJECTION may make you feel tired easily. This is because, it reduces the levels of red blood cells in your blood and may make you anemic. Consult your doctor if you experience tiredness after receiving AZADINE 100MG INJECTION. Tiredness can also occur if you have any pre-existing disease conditions such as liver or kidney impairment while receiving this medicine.

    Ques 6: Can I drive a car after receiving AZADINE 100MG INJECTION?

    Ans :AZADINE 100MG INJECTION may make you feel tired or weak. Therefore, do not drive or operate any heavy tools or machines if your ability is affected by AZADINE 100MG INJECTION.

    Ques 7: How AZADINE 100MG INJECTION is administered?

    Ans :AZADINE 100MG INJECTION will be given to you only by a doctor or a nurse beneath the skin (subcutaneously) of thighs, arms or abdomen.

    Ques 8: How to control nausea caused due to AZADINE 100MG INJECTION?

    Ans :Generally, anticancer medicines are associated with uncontrollable nausea and vomiting. To avoid this, your doctor would prescribe a suitable medicine to control them along with AZADINE 100MG INJECTION. If not, consult your doctor for a suitable anti-emetic medicine. Do not self-treat nausea.

    Overview Of Xbira 500mg Tablet

    Xbira 500mg Tablet contains Abiraterone, an androgen biosynthesis inhibitor used to treat advanced prostate cancer, particularly metastatic castration-resistant prostate cancer (mCRPC). It is prescribed when the cancer continues to grow despite treatments that lower testosterone levels. Abiraterone works by blocking the CYP17A1 enzyme, which reduces the production of androgens like testosterone that fuel prostate cancer growth, helping slow disease progression.

    Lowering androgen levels may increase aldosterone, which can cause side effects such as high blood pressure, fluid retention, and low potassium levels. To reduce these risks, Xbira is usually taken along with prednisone. Patients should inform their doctor about any existing heart, liver, or kidney conditions, high blood pressure, or other medications they are taking, as Abiraterone may interact with certain drugs and requires careful medical monitoring.


    Usage Of Xbira 500mg Tablet

    1. Metastatic castration-resistant prostate cancer (mCRPC)

    2. Metastatic high-risk castration-sensitive prostate cancer (mCSPC)

    Abiraterone is usually taken along with a corticosteroid (like prednisone) to help reduce side effects and improve treatment outcomes.

    How Xbira 500mg Tablet Works

    Xbira 500mg Tablet contains Abiraterone acetate, a prodrug that converts into abiraterone, a selective CYP17 inhibitor used in the treatment of metastatic castration-resistant prostate cancer (mCRPC). It works by blocking the CYP17A1 enzyme responsible for producing androgens such as testosterone in the adrenal glands, testes, and tumor tissues, thereby reducing hormone levels that fuel prostate cancer growth. Because this strong hormone suppression may cause side effects like fluid retention and low potassium levels, Xbira is usually prescribed along with prednisone to improve safety and treatment effectiveness.


    Side Effects Of Xbira 500mg Tablet

    Side Effects of Xbira 500mg Tablet

    Like all medications, Xbira 500mg Tablet may cause side effects. However, not everyone will experience them.

    Serious Side Effects (Seek immediate medical attention):

    • Low potassium (hypokalemia): Muscle cramps, feeling faint
    • Heart symptoms: High blood pressure, chest pain, irregular heartbeat
    • Liver symptoms: Stomach pain, nausea, jaundice (yellow skin/eyes)
    • Severe infections such as sepsis (a life-threatening complication of infection)
    • Bone fractures
    • Blood in urine
    • Adrenal insufficiency (adrenal glands not producing enough hormones)
    • Lung irritation (allergic alveolitis)

    Common Side Effects (Usually mild and temporary):

    • Swelling in legs or feet
    • Diarrhea, indigestion
    • Urinary tract infection (UTI)
    • Muscle weakness or pain
    • Rash

    Dosage Of Xbira 500mg Tablet

    The usual recommended dose of Xbira 500mg Tablet is 1000 mg once daily (4 tablets), taken on an empty stomach either 1 hour before or 2 hours after food with a glass of water. The exact dose should always be followed as prescribed by your doctor, especially if you have existing medical conditions. During treatment, regular blood tests may be advised to monitor liver and kidney function, blood counts, and lipid levels, helping ensure the medicine is safe and effective.


    Safety Advice for Xbira 500mg Tablet

    Breast Feeding

    Breast Feeding

    Unsafe

    Xbira 500mg Tablet is not for use in women, especially during breastfeeding, as it can harm the baby.

    Breast Feeding

    Alcohol

    Consult Your Doctor

    Limit or avoid alcohol, as it may worsen liver related side effects.

    Breast Feeding

    Lungs

    Unsafe

    Inform your doctor about any lung problems before starting Xbira 500mg Tablet.

    Breast Feeding

    Driving

    Unsafe

    Xbira 500mg Tablet may cause dizziness, tiredness, or high blood pressure. Avoid driving or operating machines if you feel unwell.

    Breast Feeding

    Pregnancy

    Unsafe

    Xbira 500mg Tablet is not for use in women, especially during pregnancy, as it can harm the baby.

    Storage Advice Of Xbira 500mg Tablet

  • Store at room temperature between 20°C to 25°
  • Keep out of reach of children and pets
  • Keep the container tightly closed when not in use.
  • Keep the tablets in the original packaging to protect them from moisture and light.
  • Expert Tips

  • Take Xbira 500mg Tablet (abiraterone acetate) exactly as prescribed by your doctor.
  • Always take the tablet on an empty stomach (at least 1 hour before or 2 hours after food) to avoid increased absorption and side effects.
  • Take it at the same time every day to maintain consistent drug levels in the body.
  • Patients with liver disease, heart conditions, or high blood pressure should use this medicine with caution.

  • FAQs about Xbira 500mg tablet?

    Q1. How should I take the Xbira 500mg tablet?

    Take Xbira 500mg exactly as your doctor prescribes. Swallow it on an empty stomach at least 2 hours after a meal, and do not eat anything for 1 hour after taking the tablet.

    Q2. Does Xbira 500mg Tablet interact with food or drinks?

    Yes, Xbira 500mg Tablet should be taken on an empty stomach. Eating before or after taking it can increase the drug’s absorption and raise the risk of side effects. Follow your doctor’s instructions carefully typically, no food for 2 hours before and 1 hour after taking the tablet. While it's unclear if alcohol directly interacts with abiraterone, both can affect liver function, so it's best to limit or avoid alcohol during treatment.

    Q3. Can Xbira 500mg tablet worsen liver disease?

    Yes, Xbira 500mg is not recommended for people with severe liver problems, as it can further impair liver function. Always inform your doctor about any existing liver conditions before starting this medicine.

    Q4. Can Xbira 500mg tablet cure prostate cancer?

    No, Xbira 500mg does not cure prostate cancer. It is used to manage and slow the progression of advanced or metastatic prostate cancer, especially when the cancer has spread beyond the prostate. It’s usually given with a corticosteroid to reduce side effects and is often used alongside androgen deprivation therapy (ADT) to lower testosterone levels, which helps control the disease.

    Q5. Does Xbira 500mg Tablet interact with other medicines?

    Xbira 500mg Tablet can interact with many medicines, so always inform your doctor about all prescription drugs, over-the-counter medicines, supplements, or vitamins you take. Certain medicines for seizures, tuberculosis, diabetes, mental health conditions, cough relief, and some cancer treatments may change how abiraterone works or increase side effects.

    Q6. What should I do if I miss a dose of Xbira 500mg Tablet?

    If you miss a dose, skip it and take your next dose at the regular scheduled time. Do not take a double dose to make up for the missed one. If you miss more than one dose, contact your doctor for further advice.

    Key Fact Box

    Active ingredient Abiraterone acetate
    Pharmacologic class Androgen Biosynthesis Inhibitors
    Medication category ANTI NEOPLASTICS
    Dosage forms Tablet

    Medical Advisory

      The information on the Phoenix Pharmex website is shared for educational purposes only and is not a substitute for professional medical advice or treatment. Always consult a doctor for any health-related questions. Please avoid self diagnosis or delaying medical care based on this content. Our mission is to support informed decisions not replace professional medical guidance.

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